A Handbook for DNA-Encoded Chemistry: Theory and by Robert A. Goodnow PDF

By Robert A. Goodnow

ISBN-10: 1118487680

ISBN-13: 9781118487686

This publication comprehensively describes the improvement and perform of DNA-encoded library synthesis know-how. jointly, the chapters element an method of drug discovery that provides an enticing addition to the portfolio of present hit iteration applied sciences similar to high-throughput screening, structure-based drug discovery and fragment-based screening. The book:

  • Provides a useful advisor for figuring out and utilising DNA-encoded combinatorial chemistry
  • Helps chemists generate and monitor novel chemical libraries of enormous dimension and quality
  • Bridges interdisciplinary components of DNA-encoded combinatorial chemistry – man made and analytical chemistry, molecular biology, informatics, and biochemistry
  • Shows medicinal and pharmaceutical chemists the best way to successfully develop on hand “chemical area” for drug discovery
  • Provides professional and up to date precis of said literature for DNA-encoded and DNA-directed chemistry expertise and methods

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A Handbook for DNA-Encoded Chemistry: Theory and Applications for Exploring Chemical Space and Drug Discovery by Robert A. Goodnow

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